cough. endobj They can recommend appropriate treatment options. This gives a total cumulative dose of 1,500 mg of Injectafer. There are 2 tests that your doctor will likely But its only approved for use in people with CKD who may or may not need dialysis. Iron sucrose can also be mixed in a saline solution and given through an IV over a longer time. Is the ketogenic diet right for autoimmune conditions? If youre not sure if youll need to get prior authorization for Injectafer, contact your insurance company. Keep in mind that there may be additional costs related to getting your doses of the drug at a medical facility. These are not all of the side effects that may occur. It is usually given slowly over 2 to 5 minutes or as directed by your doctor. Its not known for sure how often this condition occurred during clinical trials, or if it occurred at all during the trials. Low blood pressure. If you miss an appointment for your Injectafer dose, youll need to call your doctors office. 2005 - 2023 WebMD LLC. Injectafer is approved for use in adults who either: Injectafer contains the active drug ingredient ferric carboxymaltose. Any long-term side effects/dangers from iron infusions? If youre wondering how longside effectslast, youll be happy to know they can last just a few hours. With IV infusion, the drug is given as a slow drip into your vein over a period of time. Additional studies are ongoing to see if Injectafer is a safe and effective treatment option for these conditions. Nose or throat irritation. Get emergency medical help if you have signs of an allergic reaction to Venofer: hives, rash, itching; feeling light-headed; difficulty breathing; swelling of your face, lips, tongue, or throat. And this type of reaction is possible even if you didnt have a reaction to your first dose of the drug. This document does not contain all possible drug interactions. Why is the range so wide? What are the side effects of Venofer? For people weighing less than 50 kg, administer Injectafer in two doses of 15 mg/kg of body weight, at least 7 days apart. (For more information on Venofer, see the Injectafer vs. Venofer section above). If you have questions about the safety of breastfeeding while youre taking Injectafer, talk with your doctor. Venofer® (iron sucrose injection, USP) is available by prescription only. I hope you found answers and are feeling better now. (A class of medications describes a group of drugs that work in the same way.). Learn how to store and discard medical supplies safely. We comply with the HONcode standard for trustworthy health information. Depending on your doctors instructions and Its not known how common delayed allergic reaction might be in other people using Injectafer. The actual price youll pay for either drug depends on your insurance plan, your location, and the pharmacy you use. With IDA, you have low hemoglobin levels. Following an LSD trip, users may experience a sort of 'comedown.'. The Role of Genetics in Multifactorial Disorders, The Power of DNA Testing and Predictive Medicine, A Guide to Genome Explorer (Free Version), Whole Genome Sequencing in As Little As Three Weeks, What Diseases Can Be Detected Through Genetic Testing, Breast Cancer Genetic Testing: Pros and Cons, At Home Genetic Testing for Breast Cancer, DNA Tests for Breast Cancer Genetic Testing, What to Do When Medicines Have Side Effects, Blood Type and COVID: Infection Risk and Severity, Where Can I Get My Blood Type Checked for Free, How to Find Biological Father Through DNA. Side effectsare uncomfortable reactions to medications or drugs. If you have iron deficiency anemia (IDA), consuming moderate amounts of alcohol may be safe, if your doctor tells you its OK. (With IDA, you have a low level of red blood cells thats caused by not having enough iron.). 2 Protocol for Intravenous iron sucrose - Venofer 2.1 Dosage The total cumulative dose of Venofer should be calculated using the table below. For reasons we dont fully understand, some peoples immune system gets over-activated when the drug enters their body. Once inside your body, ferric carboxymaltose releases iron into your system. Some people only need one treatment course of Injectafer. Medically reviewed by Sanjai Sinha, MD. They have been a god send. Hes an expert in genetic testing, genetic analysis, andprecision medicine. Orofer S 50 Injection 1 Injection in 1 Packet 147. Yes, in some cases it may. If either is present, do not use the liquid. Infusions should be administered over at least 15 minutes. You can also write a reminder on your calendar. Some may be a better fit for you than others. 5 0 obj (A medication class is a group of medications that work in a similar way.). These lists contain examples of serious side effects that can occur with Injectafer, with Feraheme, or with both drugs (when taken individually). With IDA, you have low hemoglobin levels. Feraheme also comes as a liquid thats given by IV infusion. There isnt a known interaction between Injectafer and alcohol. These side effects may include constipation and diarrhea. As described just above in the Allergic reaction section, some people may have an allergic reaction after getting a dose of Injectafer. Theseside effectsmay last as long as they are undercancer treatment. The infusion concentration should not be less than 2 mg of Injectafer per mL of solution. dizziness. If you are breastfeeding, tell your doctor if you notice diarrhea or constipation in the nursing baby. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. WebMD does not provide medical advice, diagnosis or treatment. Can diet help improve depression symptoms? Do not exceed 1,500 mg of iron per dosing course. If you notice any changes to your normal blood pressure, call your doctor right away. Allergic reactions typically occur the first time your body is exposed to a drug. Data on file, American Regent, Inc. 1. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In clinical trials, serious allergic reactions occurred in 0.1% to 1.5% of people taking Injectafer. Before approving coverage for Injectafer, your insurance company may require you to get prior authorization. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. Renal elimination is negligible. This treatment course is split into two doses of the drug, which are given at least 7 days apart. HRT, like other medications, does have some side effects and these are thought to be quite common. Notify your healthcare provider of all medical conditions and any medications, including supplements you are taking. Venofer Side Effects. When the toxins are released into the air, they can be inhaled and cause irritation to the lungs. However, many people have no side effects or only have minor side effects. Injectafer is approved to treat iron deficiency anemia (IDA) in certain adults with the condition. Venofer and the Venofer logo are registered trademarks of Vifor (International) Inc., Switzerland. Together, you and your doctor can develop a treatment plan thats best for you. Throw away unused or expired drugs. It is usually given slowly over 2 to 5 minutes or as directed by your doctor. But keep in mind that in this study, delayed allergic reaction only occurred in one person. I actually was constipated after my 3rd but didn't think anything of it. Details. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: These are not all of the side effects that may occur. Muscle cramps, nausea, vomiting, strange taste in the mouth, diarrhea, constipation, headache, cough, back pain, joint pain, dizziness, or swelling of the arms/legs may occur. Source: Wolters Kluwer Health. People with IDA have low blood levels of hemoglobin. Usually, but not always, the bigger a person is the slower it takes for drugs to break down and leave the body. This medicine is sometimes given slowly, and the infusion can take up to 2.5 hours to complete. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Venofer is for use in adults and children at least 2 years old. generalized weakness. One study of just under 5000 HRT users found that 43% were affected. Its given by either intravenous (IV) infusion or slow IV injection. Venofer treatment may be repeated if iron deficiency reoccurs. After 5 weeks of treatment: This study didnt determine if either drug was better than the other. Many people using this medication do not have serious side effects.Severe dizziness or fainting (hypotension) may occur while you are receiving IV iron. And babies born to those who took Injectafer during pregnancy didnt have any major congenital anomalies (also sometimes called birth defects). During Injectafer treatment, your doctor will likely order blood tests. Potentialside effectsthat are usually mild may include, but are not limitedto: Theseside effectsmay not impact life too much and may only be temporary. You may need extra iron because of blood loss during kidney dialysis. Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat. Patients with celiac disease (gluten intolerance). And this can lead to anemia, including IDA. Examples of these side effects include dizziness and nausea. If you have questions about using Injectafer for anemia during pregnancy, talk with your doctor. If you have diarrhea while youre taking Injectafer, call your doctor. Venofer is given as an infusion into a vein. An iron infusion is a way to increase the body's iron levels quickly. (Hemoglobin is a protein thats found in your red blood cells.). Potential side effects that are usually mild may include, but are not limited to: Headache Nausea Dry Mouth Stomachache Dizziness Diarrhea Constipation These side effects may not impact life too much and may only be temporary. Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. But you dont necessarily need to eat these foods unless your doctor tells you to do so. Its not known if Injectafer is safe to take during pregnancy. It is very important that your doctor check you closely while you are receiving this medicine. TheNational Instituteof Health (NIH) and the U.S.Food and Drug Administration(FDA) monitor the side effectsof new and approved medications to ensure safety. Consult your pharmacist or local waste disposal company. Details. wAd**CgI%"nn{Oa[q{r5 If you have more questions about how Injectafer will affect your anemia, talk with your doctor. And this would give you a total cumulative Injectafer dose of 1,440 mg. Injectafer should be given in two doses. You may wonder how Injectafer compares with other medications that are prescribed for similar uses. Administer Venofer in 3 divided doses, given by slow intravenous infusion, within a 28 day period: 2 infusions each of 300 mg over 1.5 hours 14 days apart followed by one 400 mg infusion over 2.5 hours 14 days later. Or your doctor may recommend that you change your eating habits to include more iron in your diet. The study also didnt show if one treatment was worse than the other. The iron released by this drug does pass into human breast milk. However, there has been a report of delayed allergic reaction in someone receiving a second dose of Injectafer. But its not known whether this poses any risk to a child whos breastfed. Venofer injection contains iron sucrose, a form of the mineral iron. With IDA, you have anemia (low red blood cell level) thats due to not having enough iron in your body. I can't take oral supplements because they cause horrible debilitating Constipation. Both Injectafer and Venofer belong to a class of medications called iron replacement products. taste impairment. If these effects continue or worsen, tell your doctor. WARNINGS/CAUTIONS: Serious hypersensitivity reactions, including anaphylactic-type reactions (itching, hives, swelling, wheezing, difficulty breathing, fainting and/or other allergy symptoms), some of which have been life threatening and fatal, have happened in patients receiving Venofer. This medication passes into breast milk. For some people, after receiving one treatment course (two doses) of Injectafer, their IDA is resolved. Talk with your doctor. 4 0 obj Check with your pharmacist. The infusion will take between 15-30 minutes if it is given in. The information provided is not intended to replace your healthcare provider's medical advice. Venofer is indicated to treat iron deficiency anemia (IDA) in adult and pediatric patients (2 years and older) with chronic kidney disease (CKD). Canada residents can call a provincial poison control center. The researchers found that compared with their hemoglobin level before the study: But the actual price youll pay for either drug depends on your insurance plan, your location, and the pharmacy you use. Iron is an essential nutrient needed to maintain energy levels and keep you healthy. Keep all drugs out of the reach of children and pets. Iron infusions are given directly into a vein. There are currently no generic forms of either drug. So theres no recommended pediatric dosage for Injectafer. Tell your doctor if you are taking iron supplements or other iron-based oral medications. Both Injectafer and Feraheme belong to a class of medications known as iron replacement products. Does Venofer Vial interact with other drugs you are taking? The following lists contain some of the key side effects that may occur while taking Injectafer. Mental healthdisorders like depression may requireantidepressantsto treat. The recommended dosing guidelines of Injectafer for treating IDA are based on patient weight, as follows: Injectafer contains ferric carboxymaltose, which is a polymer that releases iron into the body. Iron infusion benefits. The oral form of the drug, called sucroferric oxyhydroxide and used . Injectafer comes as a liquid thats given by either intravenous (IV) infusion or slow IV injection. Vomiting. All patients receiving Venofer require periodic blood tests to monitor the amount of iron in the blood. 1xo`[kg'#KS#.#`uv:PM1+Ob`>y/8:6Ghl:y9B+-,9m[ Injectafer contains the active drug ferric carboxymaltose. Together, you and your doctor can discuss the benefits and risks of treatment options for anemia. Find comprehensive medical information for Venofer intravenous on RxList including its uses, side effects, precautions, drug interactions, overdose, pill images & warnings . Together, they can recommend ways to help you manage a body weight thats healthy for you. Brand-name medications usually cost more than generics. What is Venofer? No, Injectafer itself wont make you gain weight. Tell your doctor right away if you have any serious side effects, including: abdominal pain, chest pain, irregular heartbeat (arrhythmias), pressure in the chest, severe headache and blurred vision (hypertension), problems with your dialysis access site (graft). In the US - Call your doctor for medical advice about side effects. If needed, theyll recommend treatment, including certain medications. However, diarrhea it isnt very common in people using Injectafer. Once you have waited for 30 minutes after the injection, you may go home, providing you are feeling well. Dizziness. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Side effects from HRT depend on a number of factors: Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. On day three I had a headache and felt heavy/exhausted, which lasted a few days. If a person does not have an allergic response or any other unanticipated reactions, a doctor will administer the remaining iron. *Patients are calculated based on an estimated annual cumulative dose. In fact, Injectafer is meant for some people whose anemia didnt improve with iron pills or for people who had side effects from iron pills. Understanding what thoseside effectsare can lead to a strategy to prevent them. Find out what health conditions may be a health risk when taken with Venofer Vial Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Spacing your Injectafer doses out at least 7 days helps to reduce your risk of side effects. Youll receive doses of Injectafer from a healthcare professional at a medical facility. Injectafer contains the active drug ferric carboxymaltose, while Feraheme contains the active drug ferumoxytol. Call your healthcare provider or get medical help right away if you have symptoms of an allergic reaction, including but not limited to rash, chest pain, cough, dizziness, passing out, shortness of breath, sweating or throat tightness. (Hemoglobin is a protein thats found in red blood cells.). However, since peoples bodies react so differently to drugs, they often have to change their stance on certain drugs. With slow IV injection, the drug is given as a single, slow injection into your vein. WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. If you have a severe allergic reaction to Injectafer after youve left the medical facility where you received your dose of the drug, call your doctor right away. Serious side effects should be reported to a physician and/or PharmD for medical advice. In the study, peoples hemoglobin level was measured to check for improvement in their anemia. (One treatment course includes two doses of the drug.) Fortunately, knowing how longside effectslast can help those suffering know what to donext. <> Many patients with kidney disease cannot get enough iron from food and require injections. You may report side effects to FDA at 1-800-FDA-1088. Venofer may reduce the absorption of iron preparations taken by mouth. Joint pain. Click below for effective ways to alleviate the discomfort felt fromside effects and learn how to get a free Medication and Drug Reaction DNAReport. Injectafer contains the active drug ferric carboxymaltose. Its responsible for carrying oxygen throughout your body. Your healthcare provider will watch you closely for 30 minutes after each dose. Call your doctor right away if you have chest pain, cough or the need to cough, dizziness, passing out, shortness of breath, sweating, or throat tightness. Mild side effects of Injectafer can include:*. Common side effects of Venofer include: muscle cramps, nausea, vomiting, stomach pain, strange taste in the mouth or decreased sense of taste, diarrhea, constipation, headache, cough, sore throat, sinus pain, congestion, back pain, joint pain, dizziness, weakness, tired feeling, anxiety, ear pain, swelling of the arms/legs, or (See also Notes section.). If you have questions about the blood tests youll need to have done to monitor your anemia, talk with your doctor. It's a more immediate treatment than supplements or dietary changes. Use Venofer as ordered by your doctor. People with IDA have low blood levels of hemoglobin. Iron is also necessary for your bone marrow to build healthy new red blood cells and provide oxygen to your . All rights reserved. If you have questions about the best diet for you during Injectafer treatment, talk with your doctor. Infusion times range from less than 20 minutes to up to 4 hours. These effects typically last between 7 and 11 hours. Be ready to tell or show what was taken, how much, and when it happened. Very bad and sometimes deadly allergic side effects have rarely happened. If that happens, and your doctor thinks Injectafer is a good treatment option for you, you can receive another treatment course of the drug.
how long do venofer side effects last